May 26, 2024
In Vitro Lung Model Market

The Global In Vitro Lung Model Market Driven by Growing Need for Drug Safety Testing

The global in vitro lung model market plays a crucial role in drug development and safety testing. In vitro lung models are cell culture systems that mimic the physiological and anatomical properties of native lung tissues. They provide an effective platform for conducting pharmacological assessments, studying the absorption, distribution, metabolism, and excretion (ADME) properties of new drug candidates, and analyzing potential toxicity risks prior to clinical trials. The rising instances of drug failure during human clinical trials due to unforeseen toxicity has augmented the demand for more predictive preclinical screening assays. In vitro lung models offer a human-relevant and controlled testing environment for evaluating drug responses as well as exposure effects of inhaled toxicants. With governments across countries imposing stringent regulations on drug safety and efficacy, in vitro lung models have emerged as a valuable tool to accelerate drug development while ensuring patient safety.

The global in vitro lung model market is estimated to be valued at US$ 279.8 Mn in 2024 and is expected to exhibit a CAGR of 14.% over the forecast period 2024 to 2031, as highlighted in a new report published by Coherent Market Insights.

Market key trends:

One of the key trends prevailing in the global in vitro lung model market is the increasing utilization of 3D bioprinting techniques. 3D bioprinting allows the precise spatial deposition of living cells, biomaterials, and biochemical signals to fabricate tissue-like biological constructs in a layer-by-layer fashion. Companies are developing novel 3D bioprinted lung models featuring structure, cell composition, and functional similarities to native lung microarchitecture. Such advanced three-dimensional in vitro lung models offer an even higher predictive accuracy, thereby enhancing the translatability of preclinical research to clinical evidence. The rising popularity of 3D bioprinted organ chips is expected to open lucrative opportunities for participants of the in vitro lung model market during the forecast period.

Porter’s Analysis

Threat of new entrants: The threat of new entrants is moderate as manufacturing in vitro lung models requires specialized skills and infrastructure. However, the large market size and growing demand are attracting new players.

Bargaining power of buyers: The bargaining power of buyers is high given the availability of substitutes and buyers’ ability to negotiate lower prices for in vitro lung models.

Bargaining power of suppliers: The bargaining power of suppliers is moderate as raw material inputs can be easily sourced from multiple suppliers globally. However, suppliers specializing in lung cell lines have relatively higher bargaining power.

Threat of new substitutes: The threat of substitutes is low as in vitro lung models are replacing animal models. However, advanced computer simulations pose a threat as substitutes.

Competitive rivalry: The competitive rivalry is high owing to the presence of many global players offering in vitro lung models. Players compete on product differentiation, pricing, and services.

Key Takeaways

The global In Vitro Lung Model market is expected to witness high growth over the forecast period owing to increasing R&D spending in pharmaceutical and cosmetics industries.

North America dominates the market currently due to presence of leading players and availability of funding for R&D activities in the region. Europe is also a major market driven by stringent safety regulations for drug development.
The market is witnessing fastest growth in Asia Pacific with countries like China and India emerging as major hubs for outsourcing pharmaceutical R&D. Growing biotech industry and pharma sector in these countries is expected to drive demand.

Key players operating in the in vitro lung model market are Epithelix, MATTEK, Lonza, Emulate, AlveoliX AG, Nortis, CN Bio Innovations Ltd, MIMETAS, InSphero, ATTC Global, Tissuse GmbH and Cn Bio Innovations Limited. Major players are focusing on product launches and partnerships to strengthen their market position.

1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it